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Drug Metabolite Antifolate Drug Metabolite

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カタログ番号	製品名	別名	ターゲット
T16045	Methotrexate metabolite	DAMPA	Antifolate , Drug Metabolite
	Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.		Antifolate , Drug Metabolite
T12490	Pitavastatin lactone		Others
	Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.		Others
T37514	Hydroxy Dimetridazole		Drug Metabolite
	Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t...		Drug Metabolite
T8547	DCBA		Drug Metabolite
	DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.		Drug Metabolite
T13131	Tert-Buthyl Pitavastatin		HMG-CoA Reductase
	tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.		HMG-CoA Reductase
T3540	IMR-1A		Gamma-secretase , Drug Metabolite
	IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.		Gamma-secretase , Drug Metabolite
T9344	3-Amino-2-oxazolidinone		Others , Endogenous Metabolite
	3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone . It is always be detected as a indicator of furazolidone residues in vivo.		Others , Endogenous Metabolite
T13621	CNDAC hydrochloride		Nucleoside Antimetabolite/Analog , Others , Drug Metabolite
	CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
T12309	Omeprazole metabolite Omeprazole sulfone	Omeprazole sulphone,Omeprazole sulfone	Others
	Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.		Others
T0668	1-Aminohydantoin hydrochloride		Others
	1-Aminohydantoin hydrochloride is a major metabolite of furantoin in animal tissues. It is covalently bound to tissue proteins, released from tissues under slightly acidic conditions, and can be detected by derivatizatio...		Others
T0150	Hydroxyhexamide	(±)-Hydroxyhexamid	Potassium Channel , Drug Metabolite
	Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.		Potassium Channel , Drug Metabolite
T38003	Levofloxacin N-oxide		Others
	Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.		Others
T20723	LGE-899	Sonidegib metabolite M48,LGE 899	Drug Metabolite
	LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.		Drug Metabolite
T10138	4-Desmethoxy Omeprazole		Drug Metabolite
	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).		Drug Metabolite
T2687	Omeprazole sulfide	Omeprazole metabolite Omeprazole sulfide,Ufiprazole	Proton pump , Drug Metabolite
	Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.		Proton pump , Drug Metabolite
T8217	Enzalutamide carboxylic acid		Androgen Receptor , Drug Metabolite
	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .		Androgen Receptor , Drug Metabolite
T37600	Dasatinib N-oxide		Others
	Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].		Others
T10152	4-Methylamino antipyrine		COX , Drug Metabolite
	4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relativel...		COX , Drug Metabolite
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T1883	Des(benzylpyridyl) Atazanavi		HIV Protease
	The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.		HIV Protease
T10814	Cinacalcet metabolite M4	Rarechem AL BW 1078	Calcium Channel
	Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.		Calcium Channel
TQ0045	2-Hydroxy atorvastatin calcium salt		Drug Metabolite
	2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt which is a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).		Drug Metabolite
T0061	Clofibric acid	Chlorofibrinic acid	PPAR , Drug Metabolite
	Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.		PPAR , Drug Metabolite
T0600	10,11-Dihydrocarbamazepine	Dihydrocarbamazepine	Others
	10,11-Dihydrocarbamazepine (Dihydrocarbamazepine) is used as pharmaceutical intermediates.		Others
T5420	Cycloguanil hydrochloride	Chloroguanide Triazine	Parasite , Drug Metabolite
	Cycloguanil hydrochloride (Chloroguanide Triazine) is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, r...		Parasite , Drug Metabolite
T11641	N-Desmethyl imatinib	Imatinib metabolite N-Desmethyl imatinib,Norimatinib	Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
	N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.		Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
T13564	AZ7550		MLK , FAK , EGFR , FLT , Tyrosine Kinases , PYK2 , MNK , IGF-1R , ACK , BTK , ALK , Drug Metabolite
	AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T0109	Molsidomine	Morsydomine,SIN-10,Corvaton	NOD
	Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.		NOD
T4282	S-methyl-KE-298		MMP , Drug Metabolite
	S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.		MMP , Drug Metabolite
T8339	16α-Hydroxyprednisolone	16alpha-Hydroxyprednisolone	Others , Drug Metabolite
	16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide		Others , Drug Metabolite
T20366	Beta-Nicotyrine	Nicotyrine,alpha-Nicotyrine	Others
	beta-Nicotyrine is a tobacco alkaloids Metabolite in the liver.		Others
T4494	CLOZAPINE N-OXIDE		Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite
	Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopa...
T1234	5,5-Dimethyloxazolidine-2,4-dione	Dimethadion,Dimethadione,Dimethyloxazolidinedione	Calcium Channel
	5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.		Calcium Channel
T11205	Ent-Ezetimibe	ent-SCH 58235	Others
	Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhib...		Others
T21029	Norfluoxetine Hydrochloride	Norfluoxetine HCl	Others
	Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.		Others
T0249	N-Acetylprocainamide	NAPA,Acecainide	Potassium Channel , Sodium Channel , Drug Metabolite
	N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.		Potassium Channel , Sodium Channel , Drug Metabolite
T5158	N-Desmethylclozapine	Desmethylclozapine,Normethylclozapine,Norclozapine	Virus Protease , Dopamine Receptor , 5-HT Receptor , Opioid Receptor , AChR , Drug Metabolite
	N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
T10157	Regorafénib N-oxyde (M2)		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
T4350	Palifosfamide	ZIO-201,Isophosphamide mustard,Isophosphoramide mustard	DNA Alkylator/Crosslinker , DNA Alkylation , Drug Metabolite
	Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines excep...
T7440	P,p'-DDE	p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene	Androgen Receptor , Drug Metabolite
	p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT		Androgen Receptor , Drug Metabolite
T0050	Ampyrone	Minoazophene,Aminoantipyrin,NSC 60242,4-Aminoantipyrine,Solnapyrin-A	COX , Drug Metabolite
	Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.		COX , Drug Metabolite
T5186	Oseltamivir acid	GS 4071,oseltamivir carboxylate,Ro 64-0802	Influenza Virus , Drug Metabolite
	Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.		Influenza Virus , Drug Metabolite
T6328	Desmethyl Erlotinib	OSI-420,CP-473420,O-Desmethyl Erlotinib	EGFR , Drug Metabolite
	Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).		EGFR , Drug Metabolite
T16339	Norverapamil hydrochloride	(±)-Norverapamil hydrochloride,D591 hydrochloride	Calcium Channel , P-gp , Drug Metabolite
	Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.		Calcium Channel , P-gp , Drug Metabolite
T1327	Nortriptyline hydrochloride	Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride	Apoptosis , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor , Drug Metabolite
	Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
T4281	Endoxifen	(E/Z)-N-desmethyl-4-hydroxy Tamoxifen,(E/Z)-Endoxifen	Estrogen Receptor/ERR , Aromatase , Estrogen/progestogen Receptor , Parasite , Drug Metabolite
	(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-f...
T13564L	AZ7550 hydrochloride	AZ7550 hydrochloride (1421373-99-0 free base)	EGFR , IGF-1R
	AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).		EGFR , IGF-1R
T7894	Tazarotenic acid	AGN-190299	Others
	Tazarotenic acid (AGN-190299) is a retinoid prodrug which is converted to its active form		Others
T11986	Mebeverine acid	Mebeverine metabolite Mebeverine acid	Drug Metabolite
	Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.		Drug Metabolite
T24047	Etilevodopa hydrochloride	Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester	Others , Dopamine Receptor , Drug Metabolite
	Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.		Others , Dopamine Receptor , Drug Metabolite

Compounds

Methotrexate metabolite

T16045

Synonym: DAMPA

Target: Antifolate, Drug Metabolite

Hydroxy Dimetridazole

T37514

Synonym:

Target: Drug Metabolite

DCBA

T8547

Synonym:

Target: Drug Metabolite

Tert-Buthyl Pitavastatin

T13131

Synonym:

Target: HMG-CoA Reductase

IMR-1A

T3540

Synonym:

Target: Gamma-secretase, Drug Metabolite

3-Amino-2-oxazolidinone

T9344

Synonym:

Target: Others, Endogenous Metabolite

CNDAC hydrochloride

T13621

Synonym:

Target: Nucleoside Antimetabolite/Analog, Others, Drug Metabolite

Omeprazole metabolite Omeprazole sulfone

T12309

Synonym: Omeprazole sulphone,Omeprazole sulfone

Target: Others

1-Aminohydantoin hydrochloride

Synonym: (±)-Hydroxyhexamid

Target: Potassium Channel, Drug Metabolite

Synonym: Sonidegib metabolite M48,LGE 899

Target: Drug Metabolite

4-Desmethoxy Omeprazole

T10138

Synonym:

Target: Drug Metabolite

Omeprazole sulfide

T2687

Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole

Target: Proton pump, Drug Metabolite

Enzalutamide carboxylic acid

T8217

Synonym:

Target: Androgen Receptor, Drug Metabolite

4-Methylamino antipyrine

T10152

Synonym:

Target: COX, Drug Metabolite

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Des(benzylpyridyl) Atazanavi

T1883

Synonym:

Target: HIV Protease

Cinacalcet metabolite M4

T10814

Synonym: Rarechem AL BW 1078

Target: Calcium Channel

2-Hydroxy atorvastatin calcium salt

TQ0045

Synonym:

Target: Drug Metabolite

Clofibric acid

T0061

Synonym: Chlorofibrinic acid

Target: PPAR, Drug Metabolite

10,11-Dihydrocarbamazepine

T0600

Synonym: Dihydrocarbamazepine

Target: Others

Cycloguanil hydrochloride

T5420

Synonym: Chloroguanide Triazine

Target: Parasite, Drug Metabolite

N-Desmethyl imatinib

T11641

Synonym: Imatinib metabolite N-Desmethyl imatinib,Norimatinib

Target: Bcr-Abl, PDGFR, c-Kit, Drug Metabolite

AZ7550

T13564

Synonym:

Target: MLK, FAK, EGFR, FLT, Tyrosine Kinases, PYK2, MNK, IGF-1R, ACK, BTK, ALK, Drug Metabolite

Molsidomine

T0109

Synonym: Morsydomine,SIN-10,Corvaton

Target: MMP, Drug Metabolite

16α-Hydroxyprednisolone

T8339

Synonym: 16alpha-Hydroxyprednisolone

Target: Others, Drug Metabolite

beta-Nicotyrine

T20366

Synonym: Nicotyrine,alpha-Nicotyrine

Target: Dopamine Receptor, 5-HT Receptor, AChR, Drug Metabolite

5,5-Dimethyloxazolidine-2,4-dione

T1234

Synonym: Dimethadion,Dimethadione,Dimethyloxazolidinedione

Target: Calcium Channel

ent-Ezetimibe

T11205

Synonym: ent-SCH 58235

Target: Others

Norfluoxetine Hydrochloride

T21029

Synonym: Norfluoxetine HCl

Target: Others

N-Acetylprocainamide

T0249

Synonym: NAPA,Acecainide

Target: Potassium Channel, Sodium Channel, Drug Metabolite

N-Desmethylclozapine

T5158

Synonym: Desmethylclozapine,Normethylclozapine,Norclozapine

Target: Virus Protease, Dopamine Receptor, 5-HT Receptor, Opioid Receptor, AChR, Drug Metabolite

Regorafénib N-oxyde (M2)

T10157

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite

Palifosfamide

T4350

Synonym: ZIO-201,Isophosphamide mustard,Isophosphoramide mustard

Target: DNA Alkylator/Crosslinker, DNA Alkylation, Drug Metabolite

p,p'-DDE

T7440

Synonym: p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene

Target: Androgen Receptor, Drug Metabolite

Ampyrone

T0050

Synonym: Minoazophene,Aminoantipyrin,NSC 60242,4-Aminoantipyrine,Solnapyrin-A

Target: COX, Drug Metabolite

Oseltamivir acid

T5186

Synonym: GS 4071,oseltamivir carboxylate,Ro 64-0802

Target: Influenza Virus, Drug Metabolite

Desmethyl Erlotinib

T6328

Synonym: OSI-420,CP-473420,O-Desmethyl Erlotinib

Target: EGFR, Drug Metabolite

Norverapamil hydrochloride

T16339

Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride

Target: Calcium Channel, P-gp, Drug Metabolite

Nortriptyline hydrochloride

T1327

Synonym: Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride

Target: Apoptosis, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Norepinephrine, Autophagy, Histamine Receptor, Drug Metabolite

Endoxifen

T4281

Synonym: (E/Z)-N-desmethyl-4-hydroxy Tamoxifen,(E/Z)-Endoxifen

Target: Estrogen Receptor/ERR, Aromatase, Estrogen/progestogen Receptor, Parasite, Drug Metabolite

AZ7550 hydrochloride

T13564L

Synonym: AZ7550 hydrochloride (1421373-99-0 free base)

Synonym: Mebeverine metabolite Mebeverine acid

Target: Drug Metabolite

Etilevodopa hydrochloride

T24047

Synonym: Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester

Target: Others, Dopamine Receptor, Drug Metabolite

カタログ番号	製品名	別名	ターゲット
Fr13756	Isonicotinic acid		Endogenous Metabolite , Drug Metabolite
	Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cyt...		Endogenous Metabolite , Drug Metabolite
T13539	Allopurinol riboside		Others , Endogenous Metabolite , Parasite , Drug Metabolite
	Allopurinol riboside is a metabolite of allopurinol and shows effective activities against parasites.
T8115	Menthofuran		Others
	Menthofuran is a natural product.		Others
TN1740	Homoeriodictyol		5-HT Receptor , transporter , Sodium Channel , Drug Metabolite
	Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni...
T12095	Monomethyl fumarate		GPR , Drug Metabolite
	Monomethyl fumarate is a potent agonist of GPR109A .		GPR , Drug Metabolite
T16338	Norgestimate metabolite Norelgestromin	17-Deacetyl norgestimate,17-Deacylnorgestimate	Drug Metabolite
	Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es...		Drug Metabolite
T8175	DL-Laudanosine	Laudanosine	Others , Drug Metabolite
	DL-Laudanosine (Laudanosine) is a recognized metabolite of atracurium and cisatracurium.		Others , Drug Metabolite
T4000	(±)-Equol	Equol,(R,S)-Equol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite
	(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu...
TN1742	Homovanillyl alcohol		TNF , Drug Metabolite
	Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol displays high scavenging activities, it pr...		TNF , Drug Metabolite
T7174	Urolithin A		Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite
	Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
T2149	Vinburnine	Eburnalritardo,L-Eburnamonine,Vincamone,(-)-Eburnamonine,(-)-Vincamone	Others , Drug Metabolite
	Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.		Others , Drug Metabolite
T6293	Mycophenolate Mofetil	TM-MMF,RS 61443	Apoptosis , Dehydrogenase , Drug Metabolite
	Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).		Apoptosis , Dehydrogenase , Drug Metabolite
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T4710	3-Methoxytyramine hydrochloride	3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride)	Others , Endogenous Metabolite , Drug Metabolite
	3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human br...		Others , Endogenous Metabolite , Drug Metabolite
T0617	Nicotinamide N-oxide	Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide	c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
	Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n...
T0983	Penicillamine	d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine	Antibiotic
	Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...		Antibiotic
T5320	Tulipalin A	α-methylene-γ-butyrolactone,2-Methylenebutyrolactone	Others , Drug Metabolite
	Tulipalin A (α-methylene-γ-butyrolactone) (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.		Others , Drug Metabolite
T13808	P-Coumaric Acid Ethyl Ester	Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate	Others , Drug Metabolite
	p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato...		Others , Drug Metabolite
T5567	Tetradecanedioic acid	Tetradecanedicarboxylate	Others , Endogenous Metabolite
	Tetradecanedioic acid (Tetradecanedicarboxylate) is a long-chain fatty acid that is a type of endogenous metabolite. It can serve as a candidate biomarker for drug-drug interactions mediated by organic anion transporting...		Others , Endogenous Metabolite
T2836	Isorhamnetin	3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin	MEK , PI3K , Endogenous Metabolite
	Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...		MEK , PI3K , Endogenous Metabolite
T73915	Luisol A
	Luisol A, an aromatic tetraol and anthraquinone antibiotic analog, serves as a significant metabolite produced by an estuarine marine actinomycete from the genus Streptomyces. Additionally, it functions as an ADC (Antibo...

天然物製品

Isonicotinic acid

Fr13756

Synonym:

Target: Endogenous Metabolite, Drug Metabolite

Allopurinol riboside

T13539

Synonym:

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite

Monomethyl fumarate

T12095

Synonym:

Target: GPR, Drug Metabolite

Norgestimate metabolite Norelgestromin

T16338

Synonym: 17-Deacetyl norgestimate,17-Deacylnorgestimate

Target: Drug Metabolite

DL-Laudanosine

T8175

Synonym: Laudanosine

Target: Others, Drug Metabolite

(±)-Equol

T4000

Synonym: Equol,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Homovanillyl alcohol

TN1742

Synonym:

Target: TNF, Drug Metabolite

Urolithin A

T7174

Synonym:

Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

Vinburnine

T2149

Synonym: Eburnalritardo,L-Eburnamonine,Vincamone,(-)-Eburnamonine,(-)-Vincamone

Target: Others, Drug Metabolite

Mycophenolate Mofetil

T6293

Synonym: TM-MMF,RS 61443

Target: Apoptosis, Dehydrogenase, Drug Metabolite

Deslanoside

T8183

Synonym: Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

3-Methoxytyramine hydrochloride

T4710

Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride)

Target: Others, Endogenous Metabolite, Drug Metabolite

Nicotinamide N-oxide

T0617

Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide

Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite

Penicillamine

T0983

Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Tulipalin A

T5320

Synonym: α-methylene-γ-butyrolactone,2-Methylenebutyrolactone

Target: Others, Drug Metabolite

p-Coumaric Acid Ethyl Ester

T13808

Synonym: Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate

Target: Others, Drug Metabolite

Tetradecanedioic acid

T5567

Synonym: Tetradecanedicarboxylate

Target: Others, Endogenous Metabolite

Isorhamnetin

T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

カタログ番号	製品名
L5800	Drug Metabolite/Impurity Library	197 compounds
	A unique collection of 197 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS);
L5510	Drug-induced Liver Injury (DILI) Compound Library	1001 compounds
	A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening；
L2570	Human Metabolite Library	4454 compounds
	A unique collection of 4454 human metabolites for high-throughput, high-content screening.
L2500	Human Endogenous Metabolite Library	499 compounds
	A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;

ライブラリー

Drug Metabolite/Impurity Library

L5800

Compounds: 197

Drug-induced Liver Injury (DILI) Compound Library

L5510

Compounds: 1001

Human Metabolite Library

L2570

Compounds: 4454

Human Endogenous Metabolite Library

L2500

Compounds: 499

Gut Microbial Metabolite Library

L2540

Compounds: 607